{"id":4315,"date":"2024-04-17T06:00:00","date_gmt":"2024-04-17T13:00:00","guid":{"rendered":"https:\/\/derm-biomepharmaceuticals.com\/?p=4315"},"modified":"2024-05-08T07:47:07","modified_gmt":"2024-05-08T14:47:07","slug":"derm-biome-pharmaceuticals-topical-therapy-shows-positive-results-in-preclinical-skin-cancer-trial-drug-prevents-the-development-of-precancerous-skin-conditions-and","status":"publish","type":"post","link":"https:\/\/derm-biomepharmaceuticals.com\/de_de_formal\/derm-biome-pharmaceuticals-topical-therapy-shows-positive-results-in-preclinical-skin-cancer-trial-drug-prevents-the-development-of-precancerous-skin-conditions-and\/","title":{"rendered":"Die topische Therapie von Derm-Biome Pharmaceuticals zeigt positive Ergebnisse in pr\u00e4klinischen Hautkrebsstudien: Das Medikament verhindert die Entwicklung pr\u00e4kanzer\u00f6ser Hauterkrankungen und behandelt bestehenden Hautkrebs ohne erkennbare Nebenwirkungen."},"content":{"rendered":"

VANCOUVER, British Columbia, 17. April 2024 (GLOBE NEWSWIRE) \u2014 Die Zahl der pr\u00e4kanzer\u00f6sen Hauterkrankungen und Hautkrebserkrankungen nimmt in vielen Teilen der Welt rapide zu. Aktinische Keratose (AK) ist die h\u00e4ufigste Form der Krebsvorstufe. \u00dcber 40 Millionen Amerikaner erkranken j\u00e4hrlich an dieser Krankheit. Die Behandlung von AKs, bevor die Zellen krebsartig werden und sich auf andere K\u00f6rperteile ausbreiten, ist von entscheidender Bedeutung. F\u00fcr Patienten mit mehreren AKs sind Chemotherapie-Cremes und die photodynamische Therapie g\u00e4ngige Behandlungsoptionen. Diese Behandlungen sind zwar wirksam, haben jedoch erhebliche Nebenwirkungen wie R\u00f6tungen, Blasenbildung und Absch\u00e4len der Haut sowie langwierige und unangenehme Genesungszeiten. Der globale Markt f\u00fcr die Behandlung von aktinischer Keratose wird bis 2031 voraussichtlich ein Volumen von $10 Milliarden USD erreichen, angetrieben durch zunehmende AK-F\u00e4lle und steigende Gesundheitsausgaben.<\/p>\n\n\n\n

Derm-Biome Pharmaceuticals ist ein in Vancouver ans\u00e4ssiges biopharmazeutisches Unternehmen, das eine topische Krebsbehandlung f\u00fcr Patienten mit oder mit hohem Risiko f\u00fcr die Entwicklung mehrerer AKs entwickelt hat. In einem k\u00fcrzlich durchgef\u00fchrten UV-induzierten Hautkrebsversuch wurden M\u00e4use \u00fcber einen Zeitraum von 25 Wochen UVB-Strahlung ausgesetzt. Die verl\u00e4ngerte Exposition ahmt chronische Sonneneinstrahlung im Laufe der Zeit nach und reproduziert die allm\u00e4hliche Entwicklung von pr\u00e4kanzer\u00f6sen Hauterkrankungen zu kutanem Plattenepithelkarzinom (cSCC). Die topische Anwendung der Verbindung von Derm-Biome vor der UVB-Exposition reduzierte die Anzahl und Gr\u00f6\u00dfe pr\u00e4kanzer\u00f6ser L\u00e4sionen erheblich, w\u00e4hrend die Behandlung das Fortschreiten von Plattenepithelkarzinomtumoren blockierte.<\/p>\n\n\n\n

Fr\u00e9d\u00e9ric Couture, Forscher und Leiter der Pharmawissenschaften bei TransBIOtech: \u201eMeine Forschungsgruppe hat diese Studie mit dem Wirkstoff von Derm-Biome durchgef\u00fchrt. Der Wirkstoff zeigte eine signifikante Schutzwirkung ohne Toxizit\u00e4t oder Nebenwirkungen. Dar\u00fcber hinaus wurde das bestehende Tumorwachstum durch die medikament\u00f6se Behandlung blockiert. Wir haben tats\u00e4chlich eine Verbesserung des Aussehens der mit dem Wirkstoff behandelten Haut festgestellt.\u201c<\/p>\n\n\n\n

Dr. Poul Sorensen, Professor an der University of British Columbia und angesehener Wissenschaftler am BC Cancer Research Centre sowie CSO von Derm-Biome: \u201eDie Ergebnisse dieser Studien sind sehr vielversprechend. Wir haben unsere Verbindung anhand eines sehr aggressiven UV-induzierten Hautkrebsmodells getestet. Wir haben bei behandelten M\u00e4usen eine sehr signifikante Verringerung der Tumorzahl und starke vorbeugende Effekte beobachtet, wenn M\u00e4use mit der Verbindung vorbehandelt wurden. Diese Ergebnisse deuten darauf hin, dass unsere Verbindung gro\u00dfes Potenzial hat, ein hochwirksames und gut vertr\u00e4gliches Mittel sowohl f\u00fcr die Behandlung Und<\/em> Pr\u00e4vention von Plattenepithelkarzinomen.\u201c<\/p>\n\n\n\n

Derm-Biome-CEO Gordon Eberwein: \u201eDerzeit verf\u00fcgbare topische Behandlungen verursachen l\u00e4hmende Nebenwirkungen, die sie f\u00fcr Patienten unattraktiv machen. Es besteht ein echter Bedarf an sichereren und gezielteren topischen Therapien.\u201c<\/p>\n\n\n\n

Derm-Biome geht davon aus, diesen Sommer mit der Entwicklung topischer Formulierungen zu beginnen. Die IND-f\u00e4higen Studien sollen im vierten Quartal beginnen.<\/p>\n\n\n\n

\u00dcber Derm-Biome Pharmaceuticals, Inc.
<\/strong>Derm-Biome Pharmaceuticals, Inc. ist ein pr\u00e4klinisches biopharmazeutisches Unternehmen, das sich der Verbesserung der Hautgesundheit verschrieben hat. Wir entwickeln neuartige topische Therapien f\u00fcr entz\u00fcndliche Hautkrankheiten und pr\u00e4kanzer\u00f6se\/nicht-melanozyt\u00e4re Hautkrebsarten, die sowohl hochwirksam als auch gut vertr\u00e4glich sind.<\/p>\n\n\n\n

Derm-Biome steht kurz vor dem Start einer Seed-Finanzierungsrunde in H\u00f6he von $3M USD. F\u00fcr Investorenanfragen wenden Sie sich bitte an:<\/p>\n\n\n\n

Gordon Eberwein
geberwein@derm-biome.com<\/a>
https:\/\/derm-biomepharmaceuticals.com<\/a><\/p>\n\n\n\n

Ein Foto zu dieser Ank\u00fcndigung ist verf\u00fcgbar unter https:\/\/www.globenewswire.com\/NewsRoom\/AttachmentNg\/54b222f0-2c93-417d-8bba-33853a2dd94a<\/a><\/p>","protected":false},"excerpt":{"rendered":"

VANCOUVER, British Columbia, 17. April 2024 (GLOBE NEWSWIRE) \u2013 Die Zahl pr\u00e4kanzer\u00f6ser Hauterkrankungen und Hautkrebserkrankungen nimmt in vielen Teilen der Welt rapide zu. Aktinische Keratose (AK) ist die h\u00e4ufigste Form von Krebsvorstufen. \u00dcber 40 Millionen Amerikaner erkranken j\u00e4hrlich an dieser Erkrankung. Die Behandlung von AKs, bevor die Zellen krebsartig werden und sich auf andere K\u00f6rperteile ausbreiten, ist von entscheidender Bedeutung. F\u00fcr Patienten mit mehreren AKs sind g\u00e4ngige Behandlungsoptionen [\u2026]<\/p>","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[5],"tags":[],"class_list":["post-4315","post","type-post","status-publish","format-standard","hentry","category-recent-news"],"yoast_head":"\nDerm-Biome Pharmaceuticals\u2019 topical therapy shows positive results\u00a0in\u00a0preclinical skin cancer trial: drug prevents\u00a0the development of\u00a0precancerous skin conditions\u00a0and\u00a0treats\u00a0existing skin\u00a0cancers\u00a0with no observable\u00a0side effects. - Derm-Biome Pharmaceuticals Inc.<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/derm-biomepharmaceuticals.com\/de_de_formal\/derm-biome-pharmaceuticals-topical-therapy-shows-positive-results-in-preclinical-skin-cancer-trial-drug-prevents-the-development-of-precancerous-skin-conditions-and\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Derm-Biome Pharmaceuticals\u2019 topical therapy shows positive results\u00a0in\u00a0preclinical skin cancer trial: drug prevents\u00a0the development of\u00a0precancerous skin conditions\u00a0and\u00a0treats\u00a0existing skin\u00a0cancers\u00a0with no observable\u00a0side effects. - 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